As we head into the third full week of the college football season, some teams have already begun to make their case for a College Football Playoff spot, while others are facing early season adversity.

Week 2 saw Northern Illinois upset No. 5 Notre Dame and No. 9 Michigan fall to No. 3 Texas.

Week 3 doesn’t have many marquee matchups, but as we’ve seen, upsets can happen anytime, anywhere.

Without further ado, here are this week’s picks:

Odds via DraftKings Sportsbook

20 Arizona at 14 Kansas State (-7) – September 13, 8:00 p.m. ET

One of the week’s biggest games will be played in Manhattan on Friday night to see which Wildcats are superior. It’s Arizona’s first game against a Big 12 opponent, but oddly enough, this game doesn’t actually count towards either team’s conference record. It was scheduled years in advance, so it will go down as an out-of-conference game.

Kansas State is a touchdown favorite after escaping with a road win against Tulane in Week 2. They trailed by double digits in the first half, but a furious fourth quarter rally helped the Cats remain unbeaten. Running back D.J. Giddens has been exceptional, rushing for a combined 238 yards in two games.

Arizona is coming off of a forgettable performance against Northern Arizona. They won 22-10, but trailed at halftime and didn’t come close to covering the 37.5-point spread.

Arizona played poorly last week, but they’re better than people give them credit for. This has the potential to be a close game, and I think quarterback Noah Fifita can keep Arizona within a touchdown.

Pick: Arizona +7

4 Alabama (-16) at Wisconsin – September 14, 12:00 p.m. ET

The Crimson Tide will take a rare trip to the Midwest as they face Wisconsin on Saturday. Both squads are 2-0 and the Badgers are looking for their first win against the Tide since 1928.

Both teams have struggled with inferior opponents to start the season. Last week, Alabama was in a dog fight with South Florida. They only led 21-16 late in the fourth quarter, but three late scores for the Tide sealed the game.

Wisconsin trailed 14-13 to Western Michigan in the fourth quarter in Week 1, and in Week 2, they only led South Dakota by a touchdown heading into the final period.

Despite some rough patches, Alabama’s offense has shown the capability to put up points in a hurry, unlike Wisconsin. I’d also give the Tide’s defense the edge. Expect Alabama to play well this week and show that they belong in the College Football Playoff conversation.

Pick: Alabama -16.5

24 Boston College at 6 Missouri (-16.5) – September 14, 12:45 p.m. ET

After two dominant wins to start the season, the Eagles find themselves in the top 25. They’ve already knocked off one top 10 team on the road (Florida State) and look to make it two when they travel to Missouri.

BC quarterback Thomas Castellanos has been one of college football’s top performers thus far. He has accounted for seven total touchdowns and zero interceptions in two games. His dual threat capabilities were on full display against Florida State, where he rushed for 73 yards and a score.

Missouri hasn’t allowed a single point in either of their games. Sure, they’ve played Buffalo and Murray State, but that’s still an impressive feat. The Tigers have rushed for nine touchdowns in two games and have an elite group of wideouts led by Luther Burden III and Theo Wease Jr.

I’ll make the bold prediction that this one won’t be a shutout for the Tigers. Boston College can move the ball in the air and on the ground, and though I believe Missouri will win the game, I think the Eagles can cover.

Pick: Boston College +16.5

9 Oregon (-16.5) at Oregon State – September 14, 3:30 p.m. ET

Despite Oregon’s departure for the Big Ten, the Civil War will continue as the Ducks visit Reser Stadium to face the Beavers. Both squads are 2-0 and look vastly different than they did a year ago.

Idaho transfer Gevani McCoy is the new quarterback for Oregon State, and he has managed each game well. But the Beavers’ main focus is the rushing attack, as they have accumulated 599 yards in two games. Six of their eight touchdowns have come on the ground.

In contrast, the Ducks rely on the arm of Oklahoma transfer Dillon Gabriel for the majority of their offense. Gabriel has thrown for 623 yards, three touchdowns and no interceptions in two games.

Oregon State will have home field advantage, but they haven’t faced a team nearly as talented as the Ducks. After two close calls, Oregon is due for a dominant showing.

Pick: Oregon -16.5

Other Notable Games

16 LSU (-7) at South Carolina – September 14, 12:00 p.m. ET

Pick: LSU -7

13 Oklahoma State (-18.5) at Tulsa – September 14, 12:00 p.m. ET

Pick: Oklahoma State -18.5

18 Notre Dame (-10) at Purdue – September 14, 3:30 p.m. ET

Pick: Purdue +10

Tulane at 15 Oklahoma (-13.5) – September 14, 3:30 p.m ET

Pick: Oklahoma -13.5

5 Ole Miss (-22.5) at Wake Forest – September 14, 6:30 p.m. ET

Pick: Ole Miss -22.5

1 Georgia (-24) at Kentucky – September 14, 7:30 p.m. ET

Pick: Georgia -24